Dr. Koushik Chakrabarty
Scientist - Stem cell biology

Dr. Koushik Chakrabarty

Scientist - Stem cell biology

3rd Floor, Narayana Nethralaya, Narayana Health City

# 258/A, Bommasandra, Hosur Road,

Bengaluru, 560099 INDIA.


Contact Details
Email koushik@narayananethralaya.com
Phone +91-80-66660712

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Dr. Koushik Chakrabarty got his PhD with ‘suma cum laude’ from Ruhr University Bochum, Germany. His postdoctoral research was carried out at the Utrecht University Medical Centre. Upon completing his post-doctoral training, Dr. Chakrabarty returned to Ruhr University Bochum in 2011 as a Co-investigator in the Department of Molecular Neurobiochemistry. In 2014, he was appointed as a research faculty under the TATA trust grant award at the Centre for Neuroscience in the Indian Institute of Science in Bangalore. Dr. Chakrabarty joined the GROW Laboratory at Narayana Nethralaya, Bangalore in 2017, where he intends to harness the induced pluripotent stem cells (iPSC) technology to develop patient specific and personalized therapies.


Research Interest

Our research focuses on understanding the molecular mechanisms involved in corneal and retinal diseases and develop clinically relevant ocular disease models using human induced pluripotent stem cells (hiPSCs). Derivation of distinct corneal and retinal cell phenotypes and ocular organoids from patient iPSCs  are central to  our projects along with microscopy and a variety of molecular and cell biology tools.


Selected Publications

Shetty R, Naidu JR, Nair AP, Vaidya TA, D'Souza S, Matalia H, Deshpande V, Sethu S, Ghosh A, Chakrabarty K. Distinct ocular surface soluble factor profile in human corneal dystrophies. Ocul Surf. 2019 Nov 19. pii: S1542-0124(19)30233-2.

Chakrabarty K, Shetty R, Ghosh A. Corneal cell therapy: with iPSCs, it is no more a far-sight. Stem Cell Res Ther. 2018 Oct 25;9(1):287

Heumann R, Moratalla R, Herrero MT, Chakrabarty K, Colin RD, Garcia-Montes JR, Simola N and Morelli M. Mechanisms underlying dyskinesia in Parkinson's disease and nonpharmacological therapies. Journal of Neurochemistry, 2014 Apr 29. 

Roessler R, Smallwood S, Veenvliet JV, Pechlivanoglou P, Peng S, Chakrabarty K, and Copray S. Detailed Analysis of the Genetic and Epigenetic Signatures of iPSC-Derived Mesodiencephalic Dopaminergic Neurons. Stem cell Reports, 2014 Apr 3; 2(4):520-33.

Chakrabarty K, Von Oerthel L, Hellemons A, Clotman F, Espana A, Groot Koerkamp M, Holstege FC, Pasterkamp RJ, Smidt MP.., Genome wide expression profiling of the mesodiencephalic region identifies novel factors involved in early and late dopaminergic development, Biol Open.2012 Aug 15;1(8): 673-704

Bhattacharyya S, Khanna S, Chakrabarty K, Mahadevan A, Christopher R, Shankar SK. Anti-brain autoantibodies and altered excitatory neurotransmitters in obsessive compulsive disorder. Neuropsychopharmacology. 2009 Aug 12. 

Chakrabarty K, Heumann R. Prospective of Ras signaling in stem cells. Biological Chemistry, 2008 Jul; 389(7):791-8. Invited Review. Corresponding author.

Chakrabarty K, Serchov T, Mann S, Dietzel ID, Heumann R. Neuronal activation of Ras promotes enhancement and stabilization of dopaminergic properties in differentiating neurospheres. Eur J Neurosci. 2007 Apr; 25(7):1971-1981.

S Bhattacharyya and K Chakrabarty. Glutamatergic Dysfunction-Newer Targets for Anti-Obsessional Drugs. Recent Patents on CNS Drug Discovery Volume 2(1), Jan 2007 Pp. 47-55.

Chakrabarty K, Bhattacharyya S, Christopher R, Khanna S. Glutamatergic dysfunction in OCD. Neuropsychopharmacology. 2005 Sep; 30(9):1735-40.